20 May 2001 − − 1917

20 May 2001 − − 1917 Frederick Gerard Friedlander . 25 December

Escherichia coli Nissle 1917 distinctively modulates T-cell cycling and expansion via toll-like receptor 2 signaling.

Although the probiotic Escherichia coli strain Nissle 1917 has been proven to be efficacious for the treatment of inflammatory bowel diseases, the underlying mechanisms of action still remain elusive. The aim of the present study was to analyze the effects of E. coli Nissle 1917 on cell cycling and apoptosis of peripheral blood and lamina propria T cells (PBT and LPT, respectively). Anti-CD3-st...

یهودیان روسیه ‘ قبل وبعد از انقلاب اکتبر 1917

شکل گیری دولت روسی با توسعه ارضی قابل ملاحظه ای همراه گردید. دولت روسی این تصرف و الحاق اراضی را با دگرگون سازی عمیق و وسیع اجتماعی – اقتصادی همراه ساخت. گسترش امپراتوری روسیه با اجرای سیاست های وسیعی برای شبیه سازی اقوام گوناگون به روس ها همراه بود. یهودیان یکی از گروههای اجتماعی بودند که در جریان توسعه ارضی روسیه ‘ در مسیر اجرای سیاست یکسان سازی ‘ صدمات زیادی را متحمل شدند. سیاست های دولت روس...

Safety of probiotic Escherichia coli strain Nissle 1917 depends on intestinal microbiota and adaptive immunity of the host.

Probiotics are viable microorganisms that are increasingly used for treatment of a variety of diseases. Occasionally, however, probiotics may have adverse clinical effects, including septicemia. Here we examined the role of the intestinal microbiota and the adaptive immune system in preventing translocation of probiotics (e.g., Escherichia coli Nissle). We challenged C57BL/6J mice raised under ...

Bacteriophage therapy.

In 1917, bacteriophages were recognized as epizootic infections of bacteria and were almost immediately deployed for antibacterial therapy and prophylaxis. The early trials of bacteriophage therapy for infectious diseases were confounded, however, because the biological nature of bacteriophage was poorly understood. The early literature reviewed here indicates that there are good reasons to bel...